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Global Clinical Trials for Alzheimer’s Disease: Chapter 7. Why the Negative Studies in Alzheimer’s Disease?

Hans J. Möbius




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 |  2013-08-28 |  2013-08-28 | File type: PDF

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Regulatory approval of the first rational AD therapeutic tacrine occurred in 1993, followed by the approval of three other, AChEIs, and the NMDA antagonist memantine in 2002 (EMA) and 2003 (FDA) respectively. Since then, despite an enormous research and development effort, the past 10 years have seen a series of failures to translate pathophysiological understanding of dementia into new medicines. This includes a move away from neurotransmission to a focus on underlying ...

You can specify the type of files you want, for your device.Global Clinical Trials for Alzheimer’s Disease: Chapter 7. Why the Negative Studies in Alzheimer’s Disease?   |  Hans J. Möbius.Not only was the story interesting, engaging and relatable, it also teaches lessons.

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